• Bowed (curved) arms and legs
• Short stature
• In babies, failure to grow or gain weight as they should
• Fused skull bones. This can cause high fluid pressure in the brain, leading to headaches and bulging eyes.
• Soft, weak, or deformed bones, also called rickets
• Wider than normal wrist and ankle bones
• Breathing issues due to problems with chest and rib bones
• Painful bones and joints
• Poor muscle tone (hypotonia) that makes babies seem “floppy”
• High levels of calcium in the blood, which can lead to vomiting, constipation, weakness, and kidney damage
• Seizures
• Teeth that fall out before age 5, or unexpected tooth loss at any age
• Problem’s walking
• Bone fractures early on, especially in the feet and legs, that may be slow to heal
• Sudden, serious arthritis Many adults with HPP will remember having symptoms growing up, but never got a diagnosis as children.
Courtesy: WebMD